Coronary Artery Disease Simultaneous Intracoronary Velocity- and Pressure-Derived Assessment of Adenosine-Induced Collateral Hemodynamics in Patients With One- to Two-Vessel Coronary Artery Disease
نویسنده
چکیده
METHODS In 50 patients with oneand two-vessel coronary artery disease (CAD) undergoing percutaneous transluminal coronary angioplasty (PTCA), collateral flow index (CFI, no unit) changes and vascular resistance index (R, cm/mm Hg) changes of the collateral (Rcoll) and the distal collateral receiving (R4) vessel in response to adenosine (140 mg/min/kg IV) were measured by intracoronary (i.c.) Doppler and pressure guidewires. The variables were determined at baseline and during adenosine in patients with poor (angiographic collateral degree before PTCA ,2 of 0 to 3) and good coronary collaterals.
منابع مشابه
Collateral and collateral-adjacent hyperemic vascular resistance changes and the ipsilateral coronary flow reserve. Documentation of a mechanism causing coronary steal in patients with coronary artery disease.
OBJECTIVES The goal of this clinical study was to assess the influence of hyperemic ipsilateral, collateral and contralateral vascular resistance changes on the coronary flow velocity reserve (CFVR) of the collateral-receiving (i.e. ipsilateral) artery, and to test the validity of a model describing the development of collateral steal. METHODS In 20 patients with one- to two-vessel coronary a...
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